Na-egosi 1-12 nke 36 results

CAS O. Aha aha Isi
    935881-37-1 AR-42 (935881-37-1)

    AR-42 bụ onye mmeghe HDAC, gosipụtara ọrụ ihe omuma megide ajọ mast cell lines site na iwu ala-arụ ọrụ nke arụ ọrụ ...

    844442-38-2 AT7519 (844442-38-2)

    AT7519 bụ onye na-emechi ọtụtụ mkpụrụ ndụ cyclin-kinases (CDKs), nke nwere ike ịkpata njide cell, ịgbabata apoptosis, na inhibi ...

    602306-29-6 AZD5438 (602306-29-6)

    AZD5438 bụ onye nwere ike imechi CDK1 / 2 / 9 na IC50 nke 16 nM / 6 nM / 20 nM. Ọ dị obere ka ọ bụrụ CDK5 / 6 ma gbochie GSK3β. Oge 1.

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    865783-99-9 Briciclib (865783-99-9)

    Briciclib bụ benzyl styryl sulfone analog, na disodium phosphate ester prodrug nke ON 013100, na-enwe ike antineoplastic ọrụ.

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    1421693-22-2 CDKI-73 (1421693-22-2)

    CDKI-73 bụ onye mgbagha CDK9 dị na Ki nke 4 nM. Ọ na-egosi nhichapụ mkpụrụ ndụ na mkpụrụ ndụ CLL (LD50 = 80 nM) na nkịtị B cell na nkịtị CD34 ...

    199986-75-9 CVT-313 (NG-26) (199986-75-9)

    CVT-313 bụ onye na-eme ihe ike, nke a họọrọ, nke nwere ike ịgbanwere ya, na onye ATP-asọmpi na CDK2 (IC50 = 0.5 uM maka Cdk2 / A na Cdk2 / E; 4.2 uM maka Cdk1 / B; 21 ...

    779353-01-4 Dinaciclib (SCH727965) (779353-01-4)

    Dinaciclib (SCH727965) bụ akwụkwọ edemede na CDK2, CDK5, CDK1 na CDK9 na IC50 nke 1 nM, 1 nM, 3 nM na 4 nM, kwa ...

    942918-07-2 GSK1070916 (942918-07-2)

    GSK1070916 bụ onye na-agbachi Aurora B / C mmechi (ya na IC50 nke 3.5 nM / 6.5 nM) nke na-emepụta ngwa ngwa antitumor na mkpụrụ ndụ ọdịdị anụ ahụ na hum ...

    1346546-69-7 GSK872 (1346546-69-7)

    GSK872 bụ onye na-anabata ihe protein kinase-3 (RIP3). GSK872 mebiri TNF- na nje virus na-akpata nje na 3T3-SA fibroblasts. ...

    443797-96-4 JNJ7706621 (443797-96-4)

    JNJ-7706621 bu onye mmechi pan-CDK nke kachasi ike na CDK1 / 2 na IC50 nke 9 nM / 4 nM ma gosiputa> 6-fold selectivity for CDK1 / 2 than ...

    1073485-20-7 LDC000067 (1073485-20-7)

    LDC000067 bụ onye nhazi CDK9 nke kachasị elu na IC50 nke 44 nM, 55 / 125 / 210 /> 227 /> 227-fold selectivity over CDK2 / 1 / 4 / 6 / 7 ....

    1453834-21-3 LDC4297 (1453834-21-3)

    LDC4297 bụ onye mmeghe CDK7 (IC50 = 0.13 ± 0.06 nM maka CDK7 na IC50s n'etiti 10 nM na 10,000 nM maka ndị ọzọ nyochara CDK).

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