Na-egosi 1-12 nke 37 results

CAS O. Aha aha Isi
    552325-73-2 A-674563 (552325-73-2)

    A-674563 bụ ihe dị ike, na-ekwu okwu ọnụ okwu Akt1 nwere ihe IC50 uru nke 11nM. Na-egosiputa ihe megide PKA na CDK2 na IC50 uru ...

    1047634-63-8 Afuresertib (GSK2110183) (1047634-63-8)

    GSK2110183 bụ enweghị nkwanye okwu, nhọrọ, ATP-asọmpi na ike pan-Aktinhibitor na IC50s nke 0.08 / 2 / 2.6 nM maka Akt1 / Akt2 / Akt3 r ...

    487021-52-3 AR-A014418 (487021-52-3)

    AR-A014418 bụ ATP-asọmpi, ma na-ahọpụta GSK3β inhibitor na IC50 na Ki nke 104 nM na 38 nM, n'enweghị ihe mgbochi dị njọ na 26 ot ...

    1056901-62-2 AT13148 (1056901-62-2)

    AT13148 bu akwukwo, otutu okwu otutu okwu AGC kinase nke nwere ike pharmacodynamic na oru antitumor; AKT, p70S6K, PKA, ROCK, na SGK inhib ...

    857531-00-1 AT7867 (857531-00-1)

    AT7867 bụ onye na-eme ihe ike nke ATP-asọmpi nke Akt1 / 2 / 3 na p70S6K / PKA na IC50of 32 nM / 17 nM / 47 nM na 85 nM / 20 nM, n'otu n'otu; obere a ...

    612487-72-6 AZD1080 (612487-72-6)

    AZD1080 bụ onye na-ahọrọ, na-ekwu okwu ọnụ, ụbụrụ GSK3 nwere ike ime ihe, na-egbochi mmadụ GSK3a na GSK3β na Ki nke 6.9 nM na 31 nM, dị iche iche ...

    486424-20-8 AZD2858 (486424-20-8)

    AZD2858 bụ onye na-eme ihe na GSK-3 nke nwere IC50 nke 68 nM. AZD-2858 na-egbochi ụda phosphorylation na saịtị S396, ọ na-arụ ọrụ Wnt s ...

    1143532-39-1 AZD5636 (1143532-39-1)

    AZD5363, nke a makwaara dị ka Capivasertib, bụ onye na-ekwenye okwu okwu nke serine / threonine protein kinase AKT (protein kinase B) na pote ...

    188011-69-0 Achịcha (188011-69-0)

    Ogwu (Abrasin) bụ onye nwere ike igbochi osisi GSK-3 / Shaggy-like kinase; nhazi ala ala nke BR nke onye natara BR.

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    1007207-67-1 CH5132799 (1007207-67-1)

    CH5132799 inhibits class I PI3Ks, karịsịa PI3Ka na IC50 nke 14 nM; enweghi ike iji PI3Kβδγ, ebe o na-acho na PIK3CA mutations cell lin ...

    252935-94-7 CHIR-98014 (252935-94-7)

    CHIR-98014 bụ onye nhazi GSK3 na IC50s nke 0.65 nM na 0.58 nM maka GSK-3a na GSK-3β; ikike insulin nke glucose tr ...

    915019-65-7 Dactolisib (BEZ235) (915019-65-7)

    BEZ235 (NVP-BEZ235) bụ ATP-asọmpi PI3K na mTOR inhibitor maka p110 /// na mTOR (p70S6K) na IC50 nke 4 nM / 5 nM / 7 nM / 75 nM / 6 nM, re ...

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