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Egosi 12 pụta

CAS O. Aha aha Isi
    1146699-66-2 Avagacestat (1146699-66-2)

    Avagacestat (BMS-708163) bụ onye na-eme ihe nchịkwa y-secretase nke Aβ40 na Aβ42 na IC50 nke 0.3 nM na 0.27 nM, ...

    208255-80-5 DAPT (GSI-IX) (208255-80-5)

    DAPT (GSI-IX) bụ onye na-eme ihe nzuzo yas-secretase, nke na-egbochi mmepụta Aβ na IC50 nke 20 nM na sel HEK 293.

    1446502-11-9 Enasidenib (1446502-11-9)

    Enasidenib bụ onye nwere ike ikwu okwu, onye na-ahọpụta, onye na-emegharị ihe ntụgharị nke muta IDH2. Enasidenib, nke a maara dị ka AG-221 na CC-90007, bụ ihe dị ike na ...

    313967-18-9 FLI-06 (313967-18-9)

    FLI-06 bụ onye na-emepụta ihe ngosi nke Notch na EC50 nke 2.3 μM. FLI-06 bụ onye na-eme nchọpụta Notch na onye na-emechi ụzọ nzuzo nzuzo. FL ...

    147591-46-6 ID8 (147591-46-6)

    ID-8 bụ onye na-egbochi DYRK, ma na-akwado usoro ntinye aka nke onwe ya na embryonic na-eme ogologo oge. ID-8 bụ onye nkedo DYRK. ID-8 nwere ike kwado Wn ...

    459168-41-3 JNJ7777120 (459168-41-3)

    JNJ-7777120 bụ onye mbụ na-akwado ihe ntanetị H4 na-abụghị nke imidazole na Ki nke 4.5 nM, ihe ngosi> 1000-fold select ...

    668467-91-2 LDN-57444 (668467-91-2)

    LDN-57444 bụ onye na-eme ihe na-eme mgbanwe, nke na-eme ka onye na-ahụ maka nchekwa Uch-L1 na IC50 nke 0.88 μM, 28-fold selectivity overform Uch-L3.

    ...

    603139-19-1 Odanacatib (MK-0822) (603139-19-1)

    Odanacatib (MK 0822) bụ onye nwere ike, nhọrọ, na onye na-anọchi anya cathepsin K (mmadụ / oke bekee) na IC50 nke 0.2 nM / 1 nM, na gosipụtara h ...

    960374-59-8 ONX0914 (PR-957) (960374-59-8)

    ONX-0914 (PR-957) bụ onye inhibitor immunoproteasome nwere ike na-ahọrọ ma nwee obere mmeghachi omume maka obe maka proteasome.

    ...

    847925-91-1 RO4929097 (847925-91-1)

    RO4929097 bụ onye nchịkwa nzuzo nzuzo na IC50 nke 4 nM, na-egbochi nhazi usoro nke Aβ40 na Notch na EC50 nke 14 nM na 5 nM, na-asọpụrụ ...

    1374598-80-7 TAK875 (1374598-80-7)

    TAK-875 bụ onye na-ahọrọ GPR40 na EC50 nke 14 nM, 400-fold karịa ike acid. TAK-875 bu akwukwo ihe di iche iche, n'ezo okwu, cho ...

    209984-56-5 YO-01027 (Dibenzazepine) (209984-56-5)

    YO-01027 (Dibenzazepine) bụ onye inhibitor y-secretase na IC50 nke 2.6 nM na 2.9 nM na nyocha nke cell-free for APPL na Notch cleavage ...