Na-egosi 1-12 nke 22 results

CAS O. Aha aha Isi
    934162-61-5 A-966492 (934162-61-5)

    A-966492 bụ akwụkwọ edemede na onye nwere ike imechi nke PARP1 na PARP2 na Ki nke 1 nM na 1.5 nM, n'otu n'otu.

    328543-09-5 AG14361 (328543-09-5)

    AG14361 bụ onye na-eme ihe na-emepụta PARP-1 nwere ikikere nke 5 nM, na SW620 na mkpụrụ ndụ SW620 zuru oke, IC50 bụ 29 nM na 14 n ...

    1645286-75-4 AZ6102 (1645286-75-4)

    AZ6102 bụ onye na-emepụta TNKS1 / 2 pụrụ iche (IC50 = 3 / 1 nM) nke nwere 100-fold selectivity megide ndị ọzọ PARZ family enzymes (IC50: 0.5-3 μM) ma na-egosi ...

    1174043-16-3 AZD2461 (1174043-16-3)

    AZD2461 bụ onye edemede na PPP dị ike na IC50s nke 5 nM, 2 nM na 200 nM maka PARP1, PARP2 na PARP3. Ndabere ala ya ...

    66611-37-8 BGP-15 (66611-37-8)

    BGP-15 bụ akwụkwọ poly (rase ADR-ribose) nke na-emepụta polymerase, na-arụ ọrụ n'ime ngbanye DNA na apoptosis ...

    1207456-01-6 BMN673 (1207456-01-6)

    BMN 673 bụ onye na-eme ihe ọmụma PARP na IC50 nke 0.58 nM. Ọ bụkwa onye nwere ike imechi ihe nke PARP-2, ma ọ dịghị egbochi PARG ma nwee mmetụta dị ukwuu ...

    868540-17-4 Carfilzomib (PR171) (868540-17-4)

    Carfilzomib (PR171) bụ onye na-eme ihe nchebe na proteine ​​nke na-adịghị agbanwe agbanwe nke a na-eji mee ihe na myeloma ọtụtụ ihe na-emepụta ihe.

    134381-21-8 Epoxomicin (134381-21-8)

    Epoxomicin bụ onye na-egbochi onye na-echebe proteasome na-eme ihe na-egbochi mmadụ ime ihe na-adịghị mma, na-egbochikarị ọrụ CH-L nke proteasome 20S, w ...

    415903-37-6 Grapiprant (415903-37-6)

    Onye na-amị mkpụrụ, nke a makwaara dị ka AT-001 na CJ-023, bụ ọgwụ sitere na klas piprant. A na-enweta ihe ndị a sitere na acylsulfonamide ma na-agba ...

    133407-82-6 MG132 (133407-82-6)

    MG132 bụ proteasome nke nwere ike ịnweta na cell na-arụ ọrụ na IC50s nke 0.1 na 1.2 μM maka igbochi proteasome na calpain, ...

    1038915-60-4 MK4827 (Niraparib) (1038915-60-4)

    MK-4827 (Niraparib) bụ onye nhazi nke PARP1 / PARP2 na IC50 nke 3.8 nM / 2.1 nM; na nnukwu ọrụ na mkpụrụ ndụ cancer na mutant BRCA-1 ...

    489402-47-3 ML213 (489402-47-3)

    ML213 bụ onye nrụpụtara nhọrọ nke ọwa Kv7.2 na kv7.4, na-eme ka ọwa Kv7.2 na Kv7.4 na EC50s nke 230 na 510 nM, n'otu n'otu.

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