Echekwala Cofttek

S6 kinase & PKD-1

PS48 (1180676-32-7)

PS-48 bụ protein phosphoinositide-protein protein-kinase-1 (PDK1). PDK1 PS48 bụ obere ngwongwo agulist na Kd ọnụahịa bụ 10.3UM, ihe a kapịrị ọnụ nke PDK1 PIF-ejide akpa, dị iche na saịtị nke ATP.

Achọghị iji ọgwụgwọ eme ihe. Maka nyocha ihe naanị.

CAS: 1180676-32-7 Category

PS48 (1180676-32-7) Daha

PS48 bụ PDN1 (protein phosphoinositide-depend protein protein kinase 1) .PS48 bụ onye na-arụ ọrụ PDK1 (phosphoinositide-dependent protein kinase 1) nke na-ejikọta akpa nchekwa HM / PIF karịa saịtị ATP. PS48 bụ otu n'ime nanị ogige ndị na-atụkwasị anya n'ezie nke na-atụkwasị anya na ụlọ ọrụ na-achịkwa usoro protein na protein kinase nke na-adịghị n'akụkụ ma ọ bụ na-ejikọta ya na ebe nrụọrụ weebụ ATP.

PS48 (1180676-32-7) Smmezi

Product Name PS48
Mmekọrịta PS-48; PS 48; PS48;
Chemical Aha (2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoic acid
Klaasị ọgwụ ọjọọ PDK1 (protein phosphoinositide-dependent protein kinase 1) activator
ọcha ≥98% (HPLC)
CAS Number 1180676-32-7
molekụla Fnhazi C17H15ClO2
molekụla Wasatọ 286.75
Nkịtị Monoisotopic 286.07 g / mol
Nọmba MDL MFCD17215962
InChIKey LLJYFDRQFPQGNY-QINSGFPZSA-N
Usoro InChi InChI=1S/C17H15ClO2/c18-16-10-7-13(8-11-16)6-9-15(12-17(19)20)14-4-2-1-3-5-14/h1-5,7-8,10-12H,6,9H2,(H,19,20)/b15-12-
SMILES O = C (O) / C = C (C1 = CC = CC = C1) / CCC2 = CC = C (Cl) C = C2
ụdị ntụ ntụ
Agba ọcha na-acha ọcha
Sume Soluble na DMSO
Sịkwa akwa Temp. Mmiri, ọchịchịrị na 0 - 4 C maka obere oge (ụbọchị ruo izu) ma ọ bụ -20 C maka ogologo oge (ọnwa ruo afọ).
adị ndụ > Afọ 2 ma ọ bụrụ na echekwara ya nke ọma
njikwa Chebe na ikuku na mmiri
ngwa A protein phosphoinositide-dependent protein kinase-1 (PDK1) activator


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RIDADR NONH maka ụdị uzo niile

References:

[1]. Han F, Xue M, Chang Y, Li X, Yang Y, Sun B, Chen L. Triptolide Suppresses Glomerular Mesangial Cell Ịbawanye na Diabetic Nephropathy Na-akpakọrịta na Ntuchi nke PDK1 / Akt / mTOR Ụzọ. Nbanye J Biol Sci. 2017 Sep 21; 13 (10): 1266-1275. a: 10.7150 / ijbs.20485. 2017 eCollection. PubMed PMID: 29104493; PubMed Central PMCID: PMC5666525.

[2]. Liu Z, Ren J, Cao J, He J, Yao X, Jin C, Xue Y. Nyocha usoro nke Plk-mediated phosphoregulation na eukaryotes. Nyocha Bioinform. 2013 May; 14 (3): 344-60. a: 10.1093 / bib / bbs041. Epub 2012 Jul 31. Nyocha. PubMed PMID: 22851512.

[3]. Linli Wang et. Nyocha na usoro ọgwụ nke AlStem, 8 (1), undefined (2017-11-4)

[4]. Tohru Kimura et. Nkpọrọgwụ mkpụrụ ndụ (Dayton, Ohio), 32 (10), undefined (2014-7-6)

[5]. Zere Watanabe et. Al Pflugers Archiv: Akwụkwọ akụkọ banyere physiology nke Europe, 468 (4), undefined (2015-11-19)

1 nyochaa maka PS48 (1180676-32-7)

  1. Cofttek -

    Ọ dịghị mgbe ị nwere ahụmahụ dị otú ahụ na mbụ, The PS48 (1180676-32-7) bụ ịdị ọcha dị elu, nakwa ọrụ ahịa bụ mara mma!

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