N-Methyl-DL-asparticacid Smmezi

aha:	N-Methyl-DL-asparticacid
CAS:	17833-53-3
ọcha	98%
Usoro Molecular:	C5H9NO4
Molekụla arọ:	147.130 g / mol
Mgbaze:	189-190 ºC
Aha aha:	(2R) -2- (Methylamino) butanedioic acid
Synonyms:	N-Methylaspartate; N-Methyl-D-aspartate; NMDA
KeyInChI:	HOKKHZGPKSLGJE-GSVOUGTGSA-N
Ọkara ndụ:	N / A
Solubility:	Soluble na mmiri; Ethanol; DMSO
Ọnọdụ Nchekwa:	0 - 4 C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 C maka ogologo oge (ọnwa)
ngwa:	N-methyl-D-aspartic acid ma ọ bụ N-methyl-D-aspartate bụ amino acid sitere na nke na-arụ ọrụ dị ka agonist kpọmkwem na NMDA receptor na-eṅomi omume nke glutamate, neurotransmitter nke na-emekarị na onye na-anabata ya.
anya:	White ntụ ntụ

Kedu ihe bụ N-Methyl-DL-asparticacid (17833-53-3)?

N-Methyl-DL-Aspartic Acid (NMDLA) na-anọchi anya ngwakọta agbụrụ nke D na L enantiomers (NMDA; NMLA). Enantiomer nke ọ bụla nwere ọrụ ndu dị iche iche yana ụbara anụ ahụ/ụdị okike dị iche iche. Ya mere, onye ọ bụla enantiomer kwesịrị ịtụle iche. NMDA bụ neurotoxin a na-amụ nke ọma nke bụ agonist nke onye na-anabata NMDA ma na-ebute ndị agha ụbụrụ. A naghị ahụkarị NMDA na anụ ahụ, ebe NMLA nwere ike ịhụ ya na ụfọdụ bivalves.

N-Methyl-DL-asparticacid (17833-53-3) uru

NMDA (N-methyl-D-aspartic acid) bụ agonist ama ama maka otu klas nke ndị na-anabata glutamate, ụdị NMDA. NMDA sịntetik na-ewepụta ọrụ siri ike maka ntinye nke ihe hypothalamic na homonụ hypophyseal na anụ mamma. Ọzọkwa, a chọtara NMDA endogenous na oke, ebe ọ na-ekere òkè na ntinye nke GnRH (Gonadotropin Releasing Hormone) na hypothalamus, na nke LH (Luteinizing Hormone) na PRL (Prolactin) na pituitary gland.

N-Methyl-DL-asparticacid (17833-53-3) ngwa?

N-methyl-d-aspartic acid ma ọ bụ N-methyl-d-aspartate (NMDA) bụ amino acid ewepụtara na-arụ ọrụ dị ka agonist kpọmkwem na NMDA receptor na-eṅomi omume nke glutamate, neurotransmitter nke na-emekarị na onye nata ya. N'adịghị ka glutamate, NMDA na-ejikọta ma na-achịkwa onye na-anabata NMDA ma ọ nweghị mmetụta na ndị ọzọ na-anabata glutamate (dị ka ndị AMPA na kainate). Ndị na-anabata NMDA dị mkpa karịsịa mgbe ha na-emebiga ihe ókè n'oge, dịka ọmụmaatụ, ịwepụ mmanya na-aba n'anya n'ihi na nke a na-akpata mgbaàmà dịka mkpasu iwe na, mgbe ụfọdụ, ọkpụkpụ epileptiform.

N-Methyl-DL-asparticacid powder n'ihi na ire(Ebe ịzụta N-Methyl-DL-asparticacid ntụ ntụ na nnukwu)

Ụlọ ọrụ anyị na-enwe mmekọrịta ogologo oge na ndị ahịa anyị n'ihi na anyị na-elekwasị anya na ọrụ ndị ahịa na inye nnukwu ihe ngwaahịa. Ọ bụrụ na i nwere mmasị na anyị ngwaahịa, anyị na-agbanwe na customization nke iwu ona gị kpọmkwem mkpa na anyị ngwa ngwa ụzọ oge na iwu emesi ị ga-enwe oké akatabi okop ngwaahịa anyị na-oge. Anyị na-elekwasịkwa anya na ọrụ ndị bara uru. Anyị dị maka ajụjụ ọrụ na ozi iji kwado azụmahịa gị.

Anyị bụ ndị ọkachamara N-Methyl-DL-asparticacid ntụ ntụ soplaya ruo ọtụtụ afọ, anyị na-enye ngwaahịa na asọmpi ọnụahịa, na ngwaahịa anyị bụ nke kachasị mma ma na-enweta nyocha siri ike, nke onwe ya iji hụ na ọ dị mma maka oriri gburugburu ụwa.

References

"N-Methylaspartate - Nchịkọta Nchịkọta". Mbipụta PubChem. USA: National Center maka Biotechnology Ozi. 24 June 2005. Nchọpụta. Weghachite 9 Jenụwarị 2012.
Watkins, JC (Nọvemba 1962). "Nkwukọrịta nke ụfọdụ amino acid acid nwere ọrụ neuropharmacological." Akwụkwọ akụkọ nke ọgwụ na ọgwụ kemistry. 5 (6): 1187–1199 .
Buhusi, CV; Oprisan, SA; Buhusi, M (Eprel 2016). "Ego n'ime elekere: Oge site na nchọpụta ndakọrịta." Echiche dị ugbu a na sayensị omume. 8: 207–213 .