Alpha-GPC (28319-77-9) Manufacturer supplier factory

Alfa-GPC (28319-77-9)

April 7, 2020

Alfa GPC (alfa glycerophosphocholine), dị ka citicoline, nwekwara ike inyere ọrụ neuroprotective aka. Ọ bụ ihe mejupụtara glycerophosphate na choline.


ọnọdụ: Na Production Production
Otu: 25kg / Drum

Alfa GPC (28319-77-9) video

Alpha GPC Smmezi

aha: Alpha GPC
CAS: 28319-77-9
ọcha 50% ntụ ntụ hygroscopic ntụ ; 50% & 99% ntụ ntụ liquid 85% mmiri
Molekụla Formula: C8H20NO6P
Ọbara arọ: 257.223 g / mol
Melt Point: 142.5-143 ° C
Aha aha: Alfa GPC; Choline Alfoscerate; Alfa Glycerylphosphorylcholine
Synonyms: (R) -2,3-dihydroxypropyl (2- (trimethylammonio) ethyl) phosphate; sn-Glycero-3-phosphocholine
KeyInChI: SUHOQUVVVLNYQR-MRVPVSSYSA-N
Ọkara ndụ: 4-6 awa
Solubility: Nsogbu na DMSO, Methanol, Mmiri
Ọnọdụ Nchekwa: 0 - 4 C maka mkpirikpi oge (ụbọchị ruo izu), ma ọ bụ -20 C maka ogologo oge (ọnwa)
ngwa: Alfa GPC (Choline Alfoscerate) bụ phospholipid; ntụgharị ihu na choline biosynthesis yana etiti dị na ụzọ catabolic nke phosphatidylcholine. A na-eji Alpha GPC eme ihe dị ka Nootropic.
anya: White ntụ ntụ

Gịnị bụ Alfa GPC (28319-77-9)?

Alfa GPC (alfa glycerophosphocholine), dị ka citicoline, nwekwara ike inyere ọrụ neuroprotective aka. Ọ bụ ihe mejupụtara glycerophosphate na choline. Alfa GPC bụ kọmpụta okike nke nwekwara ike ịrụ ọrụ nke ọma na ndị ọzọ nootropics. Alfa GPC na-arụ ọrụ ngwa ngwa ma na-enyere aka na-ekesa choline na ụbụrụ ma na-eme ka mmepụta acetylcholine dịkwuo elu yana sel membrane phospholipids. Ọ ga - ekwe omume onyinye nwere ike ịbawanye ntọhapụ nke dopamine na calcium.

Alfa GPC (28319-77-9) uru

Alfa GPC wetara ya ọtụtụ uru enwere ike, otu n’ime ihe kachasị mkpa bụ na ọ ga - eme ka enwee ike ụbụrụ na cognition. Enwere ike ime Alpha GPC iji melite nhazi ebe nchekwa ma kwalite ikike mmụta. Uru uru nchekwa nchekwa enwere ike ị nweta site na alfa GPC nwere ike weghachite ncheta n'ezie, mana naanị n'ọnọdụ ụfọdụ. Alfa GPC nwekwara ike iwelie ọkwa dopamine, nke na-abara ọrụ ụbụrụ uru.

Alfa GPC bụ ọgwụ mmiri na - efe efe nke na - arụ ọrụ dị ka ihe ga - enyere Acetylcholine (ACh) na phosphatidylcholine (PC) biosynthesis ahụ niile. N'ihi profaịlụ ọrụ ya na ike ịgafe ihe mgbochi nke ụbụrụ ọbara, ọ na-eyi ka ọ bụ ihe kachasị rụọ ọrụ cholinergic, ma e jiri ya tụnyere choline na CDP-choline, a na-anabatakwa nke ọma. Nnyocha na-atụ aro na alfa-GPC na-akwado ọtụtụ ọrụ n'ime CNS gụnyere: nzaghachi mkpali akpali, na-akwado mmụta na ebe nchekwa, ma nwee ike rụọ ọrụ na ọnọdụ ahụike. N'ihi ntinye aka nke glycerophosphate, alfa-GPC pụtakwara ịkwado nhazi na ọrụ nke anụ ahụ na akwara, ma nwee ike rụọ ọrụ n'ịkwado ọrụ ụbụrụ dị mma n'oge mgbake mmerụ ahụ.

Alpha GPC (28319-77-9) Mechanism Of Action?

Alfa GPC kpaliri usoro cholinergic nke na-elekọta akụkụ akụkụ ọgụgụ isi dị ka icheta ihe na icheta ihe. Ọ bụ ebe choline kacha amasị nke na-arụ ọrụ dị ka ihe ga - eduga na Acetylcholine neurotransmitter.

Acetylcholine achọtara n'ọtụtụ ebe na ụbụrụ na ahụ, ọ bụ ọrụ maka ọtụtụ ozi kemịkalụ anyị zigara ma nata. Ọ makwaara nke ọma maka mmụta yana maka mbuze akwara wee mepụta njikọ nke ụbụrụ. Alfa GPC na-arụ ọrụ ngwa ngwa ma na-enyere aka ịnye choline na ụbụrụ ma na-eme ka mmepụta acetylcholine dịkwuo elu. Site n'inye ụbụrụ gị ọtụtụ choline ọ nwere ike ịgbanwe nke ahụ gaa na acetylcholine ma nyere aka n'ọtụtụ nsonaazụ. N'ụzọ bụ isi, a na-eji acetylcholine site na hippocampus iji mepụta ncheta.

Acetylcholine na-arụ ọrụ n'ọtụtụ ụzọ iji kwado ebe nchekwa gị. O nwekwara ike welie as ụọ ị ụ ụ ụ ụ ụ ụ ụ ikike, ikike iche echiche na iji arụmụmụ, yana okike gị. Otu ihe ahụ dịkwa mkpa maka ncheta, nhazi, na ngaghari. Etoju nke neurotransmitter ndammana nke na-eto eto. Iji jide n'aka na ị ga-ezuru kemịkal ụbụrụ a iji nwee ike mezuo ihe ọgụgụ ọrụ gị, ị ga-achọ ka ọkwa gị dị elu.

Alpha GPC (28319-77-9) Ngwa

Alfa-GPC bụ kemịkal nke ewepụtara mgbe a hụrụ abụba dị n’ime soy na osisi ndị ọzọ. Ejiri ya dika ogwu.

Na Europe alfa-GPC bụ ọgwụ ọgwụ maka ọgwụgwọ nke ọrịa Alzheimer. Ọ dị na ụdị abụọ; otu na-ewere ọnụ, ọzọ na-nyere dị ka ogbugba. Na United States alpha-GPC dị dị ka mgbakwunye nri, ọ kachasị na ngwaahịa akwalitela iji melite ebe nchekwa.

Ojiji ndị alfa-GPC gụnyere ọgwụgwọ nke ụdị ọrịa dementia, ọrịa strok, na “mini-stroke” (trensient ischemic Attack, TIA). A na-ejikwa Alfa-GPC emeziwanye ebe nchekwa, ikike iche echiche, na mmụta.

Alpha GPC powder n'ihi na ire(Ebe ị ga-azụta Alfa GPC ntụ ntụ na nnukwu)

Companylọ ọrụ anyị na ndị ahịa anyị na-enwe mmekọrịta ogologo oge n'ihi na anyị na-elekwasị anya n'ọrụ ndị ahịa ma na-enye nnukwu ngwaahịa. Ọ bụrụ na ị nwere mmasị na ngwaahịa anyị, anyị na-agbanwe agbanwe na nhazi nke iwu iji kwekọọ na mkpa gị kpọmkwem na oge ngwụsị nke oge anyị na ntinye iwu nke nkwa ị ga-enwe nnukwu uto nke ngwaahịa anyị n'oge. Anyị na-elekwasịkwa anya n'ọrụ bara uru. Anyị dị maka ajụjụ ọrụ na ozi iji kwado azụmahịa gị.

Anyị bụ ndị na - eweta ngwaahịa Alpha GPC ntụ ntụ ọkachamara ruo ọtụtụ afọ, anyị na - enye ọnụahịa maka ọnụahịa asọmpi, ngwaahịa anyị dịkwa mma kachasị elu ma na - anwale nnwale siri ike iji hụ na ọ dị mma maka oriri gburugburu ụwa.

References

  • Ricci A, Bronzetti E, Vega JA, Amenta F. Oral choline alfoscerate na-agbada mfu afọ nke ihe nke mossy na akwara dị n'ụkwụ hippocampus. Mech Aging Dev. 1992; 66 (1): 81-91. PubIDed PMID: 1340517.
  • Amenta F, Ferrante F, Vega JA, Zaccheo D. ogologo oge choline alfoscerate ọgwụgwọ na-emetụta mgbanwe microanatomical afọ ndụ na ụbụrụ oke. Prog Neuropsychopharmacol Biol Psychiatry. 1994 Septemba; 18 (5): 915-24. PubIDed PMID: 7972861.
  • Amenta F, Del Valle M, Vega JA, Zaccheo D. Mgbanwe usoro metụtara afọ na oke cerebellar cortex: mmetụta nke ọgwụgwọ choline alfoscerate. Mech Aging Dev. 1991 Maachị 2; 61 (2): 173-86. PubIDed PMID: 1824122.