Sodium Citicoline (CDP Choline Sodium)(33818-15-4) Smmezi
| aha: | Sodium Citicoline (CDP Choline Sodium) |
| CAS: | 33818-15-4 |
| ọcha | 98% |
| Usoro Molecular: | C14H25N4NaO11P2 |
| Molekụla arọ: | 510.308 g / mol |
| Melt Point: | > 240 Celsius |
| Aha aha: | Sodium Citicoline; Cdp-choline sodium |
| Synonyms: | Sodium [[(2S,3R,4S,5S)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]2-(trimethylazaniumyl)ethyl phosphate |
| KeyInChI: | YWAFNFGRBBBDa-KDVMHAGBSA-M |
| Ọkara ndụ: | 56 awa |
| Solubility: | Nsogbu na DMSO, Mmiri (Obere) |
| Ọnọdụ Nchekwa: | Akọrọ, ọchịchịrị na 0 - 4 C maka obere oge (ụbọchị ruo izu) ma ọ bụ -20 C maka ogologo oge (ọnwa ruo afọ). |
| ngwa: | Citicoline sodium bụ onye na-ahụ maka neuroprotective na emeju nri |
| anya: | White edozi ntụ ntụ |
Sodium Citicoline (33818-15-4) NMR ụdịdị dị iche iche
Ọ bụrụ na ịchọrọ COA, MSDS, HNMR maka ụdị ngwaahịa ọ bụla na ozi ndị ọzọ, biko kpọtụrụ anyị njikwa ahia.
Gịnị bụ Sodium Citicoline (CDP Choline Sodium)(33818-15-4) ?
Citicoline Sodium (CDP-choline Sodium, cytidine 5'-diphosphocholine) ntụ ntụ bụ mmiri na-edozi ahụ nke na-arụ ọrụ dị ka ihe na-ebute ma choline na cytidine n'ime ụbụrụ (nke mechara gbanwee na uridine). N'ebe ụmụ mmadụ nọ, Citicoline Sodium bụ ihe dị mkpa na-edozi ahụ dịka ọrụ ya na-ebelata ihe ize ndụ nke ntụpọ akwara, ọrịa imeju na-agba abụba, na ọrịa ndị ọzọ. CDP-choline sodium bụ otu n'ime ha phospholipids nwere choline atọ nke enwere ike ịgbakwunye ọnụ (abụọ ndị ọzọ bụ alfa-GPC na phosphatidylcholine).
Sodium Citicoline (CDP Choline Sodium)(33818-15-4) uru
CDP-choline na-eme ka biosynthesis nke bughi phospholipids rụọ ọrụ na membranes neuronal, na-eme ka ụbụrụ ụbụrụ na-abawanye ma na-arụ ọrụ na ọkwa dị iche iche. N'ihi ya, a nwalere ya na nyocha CDP-choline na-abawanye ogo noradrenaline na dopamine na CNS.
Ihe mgbakwunye a bụ maka igbochi ma ọ bụ ịgwọ nsogbu ebe nchekwa metụtara ịka nká n'ihi eziokwu ahụ bụ na mkpụrụ ndụ abụọ ọ na-enye bụ neuroprotective na nwere ike welie mmụta. Ọ bụ ezie na ọ dị ka ọ dị irè karịa phosphatidylcholine (PC) na ọrụ a, n'akụkụ ụfọdụ n'ihi na ọ na-amụbakwa PC synthesis na ụbụrụ, ike ya dịtụ ka nke Alpha-GPC.
Sodium Citicoline (CDP Choline Sodium)(33818-15-4) ojiji
CDP-choline nwere ụfọdụ ojiji ndị ọzọ metụtara mmekọrịta. A na-ejikarị ya eme ihe dị ka ihe ncheta ncheta na ntorobịa, mana n'agbanyeghị ụfọdụ ọmụmụ ihe na-egosi na nke a ga-ekwe omume site na ọnụ CDP-choline, ọ dịghị ihe ọmụmụ mmadụ na-eto eto n'oge a. Otu nnyocha achọpụtawo mmụba nke nlebara anya na obere CDP-choline (nke kwesịrị imeghachi), na CDP-choline nwere ike ịnwe ọrụ dị ka ihe na-eri ahụ na-eri ahụ megide cocaine na (ihe àmà mbụ na-egosi) nri.
Sodium Citicoline (CDP Choline Sodium)(33818-15-4) ngwa
Citicoline Sodium (CDP Choline Sodium) ntụ ntụ bụ onye na-ahụ maka neuroprotective. Ọ na - eme site na ịkwalite nkwukọrịta cellular, na - akpali akpali njikọ nke SAMe, yana ịba ụba glucose metabolis. Citicoline Sodium (CDP Choline Sodium) ntụ ntụ bụ nucleotide na-emekarị; n'etiti n'etiti ụzọ nke lecitin biosynthesis. Neuroprotective. A na-eji ya na ọgwụgwọ ọrịa strok na isi trauma. Neuroprotective mmepụta ihe. Citicholine na-egosipụta mmetụta nchedo na ọrịa ụbụrụ nke ụbụrụ, mmerụ traumatic ụbụrụ, na nsogbu ncheta. Na nso nso a gosipụtara nrụpụta ọrụ megide mgbaka mgbe enyere ya na AchEIs (Acetylcholinesterase inhibitor). E gosipụtara Neuroprotective, ọrụ acnticonvulsant na mmetụta nkwụsịtụ na ọgwụ nke 150mg / kg na oke. Egosiputa nchebe megide aluminom butere mmerụ uche na oke na-ebelata ogo glutamate, oxidativestress na NO overproduction in the hippocampus.
Sodium Citicoline (CDP Choline Sodium)(33818-15-4) powder n'ihi na ire
(Ebe tozụta Sodium Citicoline (CDP Choline Sodium)(33818-15-4) ntụ ntụ na nnukwu)
Ụlọ ọrụ anyị na-enwe mmekọrịta ogologo oge na ndị ahịa anyị n'ihi na anyị na-elekwasị anya na ndị ahịa ọrụ na inye nnukwu ngwaahịa. Ọ bụrụ na i nwere mmasị na anyị ngwaahịa, anyị na-agbanwe na customization nke iwu ona gị kpọmkwem mkpa na anyị ngwa ngwa ụzọ oge na iwu emesi ị ga-enwe oké akatabi okop ngwaahịa anyị na-oge. Anyị na-elekwasịkwa anya na ọrụ ndị bara uru. Anyị dị maka ajụjụ ọrụ na ozi iji kwado azụmahịa gị.
Anyị bụ ndị ọkachamara Sodium Citicoline (CDP Choline Sodium)(33818-15-4) ntụ ntụ soplaya ruo ọtụtụ afọ, anyị na-enye ngwaahịa na asọmpi ọnụahịa, na ngwaahịa anyị bụ nke kachasị mma ma na-enweta nyocha siri ike, nke onwe ya iji hụ na ọ dị mma maka oriri gburugburu ụwa.
References
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[2] Jiang JJ, Xie YM, Zhang Y, Zhang YK, Wang ZM, Han B. [Njirimara ọgwụ ọgwụ nke Shuxuening injection na ọgwụgwọ nke nchọpụta ọrịa infarction dabeere na ndebanye aha]. Zhongguo Zhong Yao Za Zhi. 2016 Dec; 41 (24): 4516-4520. doi: 10.4268 / cjcmm20162407. Ndị China. PubMed PMID: 28936832.
[3] Liu Y, Wang J, Xu C, Chen Y, Yang J, Liu D, Niu H, Jiang Y, Yang S, Ying H. Nnukwu arụmọrụ ọtụtụ CDP-choline nke CDP na-eweta. Appl Microbiol Biotechnol. 2017 Feb; 101 (4): 1409-1417. doi: 10.1007 / s00253-016-7874-0. Epub 2016 Ọkt 13. PubMed PMID: 27738720.
[4] Giménez R, Raïch J, Aguilar J (Nov 1991). "Ngbanwe nke ụbụrụ striatum dopamine na ndị nabatara acetylcholine na-akpata site na ọgwụgwọ CDP na-adịghị ala ala nke ụmụ oke na-eme agadi". Akwụkwọ akụkọ British Journal of Pharmacology. 104 (3): 575–8. ma ọ bụ: 1111 / j.1476-5381.1991.tb12471.x. PMC1908237. PMID1839138.
[5] Tardner, P. (2020-08-30). "Ojiji nke citicoline maka ọgwụgwọ nke ịda mba na mmerụ ahụ: Meta-analysis of pharmacological literature • International Journal of Environmental Science & Technology". Akwụkwọ bụ International Journal of Science & Technology. Weghachite 2020-08-31.
