Kacha mma Citicoline Sodium (33818-15-4) Emeputa - Cofttek

Sodium Citicoline (33818-15-4)

Nwere ike 8, 2021

Cofttek bụ onye nrụpụta ntụ ntụ kacha mma Citicoline Sodium (CDP Choline Sodium) na China. Ụlọ ọrụ anyị nwere sistemụ njikwa mmepụta zuru oke (ISO9001 & ISO14001), yana ikike mmepụta kwa ọnwa nke 220kg.

 


ọnọdụ: Na Production Production
Otu: 1kg / akpa, 25kg / Drum

Sodium Citicoline (CDP Choline Sodium)(33818-15-4) Smmezi

aha: Sodium Citicoline (CDP Choline Sodium)
CAS: 33818-15-4
ọcha 98%
Usoro Molecular: C14H25N4NaO11P2
Molekụla arọ: 510.308 g / mol
Melt Point: > 240 Celsius
Aha aha: Sodium Citicoline; Cdp-choline sodium
Synonyms: Sodium [[(2S,3R,4S,5S)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]2-(trimethylazaniumyl)ethyl phosphate
KeyInChI: YWAFNFGRBBBDa-KDVMHAGBSA-M
Ọkara ndụ: 56 awa
Solubility: Nsogbu na DMSO, Mmiri (Obere)
Ọnọdụ Nchekwa: Akọrọ, ọchịchịrị na 0 - 4 C maka obere oge (ụbọchị ruo izu) ma ọ bụ -20 C maka ogologo oge (ọnwa ruo afọ).
ngwa: Citicoline Sodium bụ ihe na-egbochi neuroprotective na mgbakwunye nri
anya: White edozi ntụ ntụ

 

Sodium Citicoline (33818-15-4) NMR ụdịdị dị iche iche

Sodium Citicoline (33818-15-4) NMR ụdịdị dị iche iche

Ọ bụrụ na ịchọrọ COA, MSDS, HNMR maka ụdị ngwaahịa ọ bụla na ozi ndị ọzọ, biko kpọtụrụ anyị njikwa ahia.

 

Gịnị bụ Sodium Citicoline (CDP Choline Sodium)(33818-15-4) ?

Citicoline Sodium (CDP-choline Sodium, cytidine 5a-diphosphocholine) ntụ ntụ bụ mmiri na-edozi mmiri nke na-eje ozi dị ka ihe bu ụzọ ma choline na cytidine n'ime ụbụrụ (nke mechara tụgharịa gaa uridine). Nye ụmụ mmadụ, Citicoline Sodium bụ ihe dị mkpa dị mkpa dị ka ọrụ ya na mbenata ntụpọ neural tube, ọrịa imeju abụba, na ọrịa ndị ọzọ. CDP-choline Sodium bụ otu n'ime phospholipids nwere choline atọ nwere ike iji ọnụ kwupụta (abụọ ndị ọzọ bụ alpha-GPC na phosphatidylcholine).

 

Sodium Citicoline (CDP Choline Sodium)(33818-15-4) uru

CDP-choline na-eme ka biosynthesis nke bughi phospholipids rụọ ọrụ na membranes neuronal, na-eme ka ụbụrụ ụbụrụ na-abawanye ma na-arụ ọrụ na ọkwa dị iche iche. N'ihi ya, a nwalere ya na nyocha CDP-choline na-abawanye ogo noradrenaline na dopamine na CNS.

A na-edozi ndozi a iji gbochie ma ọ bụ na-emeso nsogbu mberede nke ebe nchekwa nke metụtara ịka nká n'ihi eziokwu ahụ bụ na mkpụrụokwu abụọ ọ na-ekwupụta bụ ndị na-adịghị edozi ma nwee ike ịmalite ịmụ ihe. Ọ bụ ezie na o yiri ka ọ dị irè karịa phosphatidylcholine (PC) na ọrụ a, n'akụkụ ụfọdụ site na ịmalite ịbịakwute PC na ụbụrụ, ike ya dịka nke Alpha-GPC.

 

Sodium Citicoline (CDP Choline Sodium)(33818-15-4) ojiji

CDP-choline nwere ụfọdụ ojiji ndị ọzọ metụtara mmekọrịta. A na-ejikarị ya eme ihe dị ka ihe ncheta ncheta na ntorobịa, mana n'agbanyeghị ụfọdụ ọmụmụ ihe na-egosi na nke a ga-ekwe omume site na ọnụ CDP-choline, ọ dịghị ihe ọmụmụ mmadụ na-eto eto n'oge a. Otu nnyocha achọpụtawo mmụba nke nlebara anya na obere CDP-choline (nke kwesịrị imeghachi), na CDP-choline nwere ike ịnwe ọrụ dị ka ihe na-eri ahụ na-eri ahụ megide cocaine na (ihe àmà mbụ na-egosi) nri.

 

Sodium Citicoline (CDP Choline Sodium)(33818-15-4) ngwa

Citicoline Sodium (CDP Choline Sodium) ntụ ntụ bụ onye na-ahụ maka neuroprotective. Ọ na - eme site na ịkwalite nkwukọrịta cellular, na - akpali akpali njikọ nke SAMe, yana ịba ụba glucose metabolis. Citicoline Sodium (CDP Choline Sodium) ntụ ntụ bụ nucleotide na-emekarị; n'etiti n'etiti ụzọ nke lecitin biosynthesis. Neuroprotective. A na-eji ya na ọgwụgwọ ọrịa strok na isi trauma. Neuroprotective mmepụta ihe. Citicholine na-egosipụta mmetụta nchedo na ọrịa ụbụrụ nke ụbụrụ, mmerụ traumatic ụbụrụ, na nsogbu ncheta. Na nso nso a gosipụtara nrụpụta ọrụ megide mgbaka mgbe enyere ya na AchEIs (Acetylcholinesterase inhibitor). E gosipụtara Neuroprotective, ọrụ acnticonvulsant na mmetụta nkwụsịtụ na ọgwụ nke 150mg / kg na oke. Egosiputa nchebe megide aluminom butere mmerụ uche na oke na-ebelata ogo glutamate, oxidativestress na NO overproduction in the hippocampus.

 

Sodium Citicoline (CDP Choline Sodium)(33818-15-4) powder n'ihi na ire

(Ebe tozụta Sodium Citicoline (CDP Choline Sodium)(33818-15-4) ntụ ntụ na nnukwu)

Companylọ ọrụ anyị na ndị ahịa anyị na-enwe mmekọrịta ogologo oge n'ihi na anyị na-elekwasị anya n'ọrụ ndị ahịa ma na-enye nnukwu ngwaahịa. Ọ bụrụ na ị nwere mmasị na ngwaahịa anyị, anyị na-agbanwe agbanwe na nhazi nke iwu iji kwekọọ na mkpa gị kpọmkwem na oge ngwụsị nke oge anyị na ntinye iwu nke nkwa ị ga-enwe nnukwu uto nke ngwaahịa anyị n'oge. Anyị na-elekwasịkwa anya n'ọrụ bara uru. Anyị dị maka ajụjụ ọrụ na ozi iji kwado azụmahịa gị.

Anyị bụ ndị ọkachamara Sodium Citicoline (CDP Choline Sodium)(33818-15-4) onye na-ebu ntụ ntụ ruo ọtụtụ afọ, anyị na-enye ngwaahịa na asọmpi ọnụahịa, ngwaahịa anyị dịkwa mma kachasị mma ma na-anwale ule siri ike, nke onwe iji hụ na ọ dị mma maka oriri gburugburu ụwa.

 

References

[1] Tyurenkov IN, Kurkin DV, Bakulin DA, Volotova EV, Chafeev MA. [Ọrụ Cerebroprotective nke metformin, gosogliptin, citicoline na ọkà mmụta GPR119 agonist dị na cerebral ischemia n'okpuru nnwale ọrịa shuga mellitus]. Zh Nevrol Psikhiatr Im SS Korsakova. 2017; 117 (12. Vyp. 2): 53-59. doi: 10.17116 / jnevro201711712253-59. Rọshịan. PubIDed PMID: 29411746.

[2] Jiang JJ, Xie YM, Zhang Y, Zhang YK, Wang ZM, Han B. [Njirimara ọgwụ ọgwụ nke Shuxuening injection na ọgwụgwọ nke nchọpụta ọrịa infarction dabeere na ndebanye aha]. Zhongguo Zhong Yao Za Zhi. 2016 Dec; 41 (24): 4516-4520. doi: 10.4268 / cjcmm20162407. Ndị China. PubMed PMID: 28936832.

[3] Liu Y, Wang J, Xu C, Chen Y, Yang J, Liu D, Niu H, Jiang Y, Yang S, Ying H. Nnukwu arụmọrụ ọtụtụ CDP-choline nke CDP na-eweta. Appl Microbiol Biotechnol. 2017 Feb; 101 (4): 1409-1417. doi: 10.1007 / s00253-016-7874-0. Epub 2016 Ọkt 13. PubMed PMID: 27738720.

[4] Giménez R, Raïch J, Aguilar J (Nov 1991). "Ngbanwe nke ụbụrụ striatum dopamine na ndị nabatara acetylcholine na-akpata site na ọgwụgwọ CDP na-adịghị ala ala nke ụmụ oke na-eme agadi". Akwụkwọ akụkọ British Journal of Pharmacology. 104 (3): 575–8. ma ọ bụ: 1111 / j.1476-5381.1991.tb12471.x. PMC1908237PMID1839138.

[5] Tardner, P. (2020-08-30). "Ojiji nke citicoline maka ọgwụgwọ nke ịda mba na mmerụ ahụ: Meta-analysis of pharmacological literature • International Journal of Environmental Science & Technology". Akwụkwọ bụ International Journal of Science & Technology. Weghachite 2020-08-31.

 


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