NMN ntụ ntụ (1094-61-7)

April 7, 2020

Nicotinamide Mononucleotide, nke a makwaara ("NMN" na "β-NMN") bụ nucleotide sitere na ribose na nicotinamide Dị ka nicotinamide riboside, NMN bụ ihe mgbapụta nke niacin, ụmụ mmadụ nwere enzymes nke nwere ike iji NMN mepụta nicotinamide adenine dinucleotide ( NADH).

 


ọnọdụ: Na Production Production
Otu: 1kg / akpa, 25kg / Drum

NMN ntụ ntụ (1094-61-7) video

 

NMN ntụ ntụ Smmezi

aha: Nic-Nicotinamide Mononucleotide (NMN)
CAS: 1094-61-7
ọcha 98%
Usoro Molecular: C11H15N2O8P
Molekụla arọ: 334.2208 g / mol
Melt Point: > 96 Celsius
Aha aha: ((2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate
Synonyms: Nicotinamide Mononucleotide; NMN; β-NMN; Nic-Nicotinamide mononucleotide
KeyInChI: DAYLJWODMCOQEW-TURQNECASA-N
Ọkara ndụ: N / A
Solubility: Nsogbu na DMSO, Methanol, Mmiri
Ọnọdụ Nchekwa: 0 - 4 C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 C maka ogologo oge (ọnwa)
ngwa: Nicotinamide mononucleotide (NMN) bụ usoro nke vitamin-B nke na-eme ka ahụike dịkwuo elu ma na-adị ogologo oge site na ije ozi dịka NAD +, kọlụm nke na-arụ ọrụ dị mkpa na mmepụta ume, metabolism, na nkwụpụta mkpụrụ ndụ na ahụ.
anya: White ntụ ntụ

 

NMN (1094-61-7) NMR ụdịdị dị iche iche

NMN (1094-61-7) - NMR ụdịdị dị iche iche

Ọ bụrụ na ịchọrọ COA, MSDS, HNMR maka ụdị ngwaahịa ọ bụla na ozi ndị ọzọ, biko kpọtụrụ anyị njikwa ahia.

 

Gini bu β-Nicotinamide Mononucleotide (NMN) CAS 1094-61-7?

Nicotinamide Mononucleotide, nke a makwaara ("NMN" na "β-NMN") bụ nucleotide sitere na ribose na nicotinamide Dị ka nicotinamide riboside, NMN bụ ihe mgbapụta nke niacin, ụmụ mmadụ nwere enzymes nke nwere ike iji NMN mepụta nicotinamide adenine dinucleotide ( NADH). Ebe ọ bụ na NADH bụ onye na-arụ ọrụ maka usoro n'ime mitochondria, maka sirtuins, na PARP, NMN ka a mụọla na ụdị anụmanụ dị ka onye nwere ike igbochi ọgwụ na ịka nká.

 

β-Nicotinamide Mononucleotide (NMN) CAS 1094-61-7 uru

Nnyocha nyocha nke ime agadi egosila na mgbakwunye na NMN, bụ isi NAD + n'etiti, na-arụ ọrụ iji belata ọdịda metabolic metụtara afọ na ibelata ọganihu nke ọtụtụ ọrịa metụtara afọ. NMN nwere mmetụta bara uru na mmepụta nke ike na ọkwa cellular, na-eme ka nnabata nke glucose dị, belata mbufụt, na-enyere aka ichekwa usoro mgbasa, na-edozi DNA, ma nwee mmetụta bara uru na ichebe ọrụ ọgụgụ isi. NMN egosipụtakwala ikike dịka onye na-ahụ maka ọgwụgwọ megide ọrịa neurodegenerative dịka nke ịka nká. Mmeju na NMN nwere ike ịba uru na ichebe ntachi obi na agagharị. Ichebe ọrụ nke usoro ndị a dịgasị iche n'ofe ahụ na-akwalite ahụike na ịdị ogologo ndụ ma na-eme ka ndụ dịkwuo mma ka ịka nká na-aga n'ihu.

 

-Nicotinamide Mononucleotide (NMN) CAS 1094-61-7 Usoro nke ime ihe?

β-Nicotinamide Mononucleotide (NMN) bụ etiti nke NAD + biosynthesis nke emepụtara site na nicotinamide site na nicotinamide phosphoribosyltransferase (NAMPT) ma kpọọkwa ya NMN ma ọ bụ nicotinamide ribotide. N'ime nnyocha ndị emere n'oge na-adịbeghị anya banyere ngwa NMN iji gbochie na nchoputa nke ọrịa ndị na-adabere na afọ dịka ọrịa shuga, ọrịa neurodegenerative, ọrịa obi na wdg, ọ ghọwo otu n'ime ndị na-ahụ maka biomarkers kachasị na mkparịta ụka maka ịka nká, n'oge na-adịbeghị anya.

 

-Nicotinamide Mononucleotide (NMN) CAS 1094-61-7 ngwa

β-Nicotinamide Mononucleotide (NMN) nwere mmetụta bara uru na metabolism n'ime ahụ niile, gụnyere nsonaazụ dị mma na akwara ọkpụkpụ, ọrụ imeju, oke ọkpụkpụ, ọrụ anya, insulin na-ahụ anya, ọrụ mgbochi ọrịa, oke ahụ, yana ọkwa ọrụ.

 

NMN powder n'ihi na ire(Ebe ị ga-azụta β-Nicotinamide Mononucleotide (NMN) ntụ ntụ na nnukwu)

Companylọ ọrụ anyị na ndị ahịa anyị na-enwe mmekọrịta ogologo oge n'ihi na anyị na-elekwasị anya n'ọrụ ndị ahịa ma na-enye nnukwu ngwaahịa. Ọ bụrụ na ị nwere mmasị na ngwaahịa anyị, anyị na-agbanwe agbanwe na nhazi nke iwu iji kwekọọ na mkpa gị kpọmkwem na oge ngwụsị nke oge anyị na ntinye iwu nke nkwa ị ga-enwe nnukwu uto nke ngwaahịa anyị n'oge. Anyị na-elekwasịkwa anya n'ọrụ bara uru. Anyị dị maka ajụjụ ọrụ na ozi iji kwado azụmahịa gị.

Anyị bụ ọkachamara β-Nicotinamide Mononucleotide (NMN) ntụ ntụ maka ọtụtụ afọ, anyị na-enye ngwaahịa maka ọnụahịa asọmpi, ngwaahịa anyị dịkwa mma kachasị elu ma na-anwale nnwale siri ike iji hụ na ọ dị mma maka oriri gburugburu ụwa.

 

References

  • Kiss T, Balasubramanian P, Valcarcel-Ares MN, Tarantini S, Yabluchanskiy A, Csipo T, Lipecz A, Reglodi D, Zhang XA, Bari F, Farkas E, Csiszar A, Ungvari Z. Nicotinamide mononucleotide (NMN) na-egosipụta nrụgide oxidative. ma na-azọputa ikike angiogenic na mkpụrụ ndụ ụbụrụ nke ọrịa ụbụrụ: usoro nke nwere ike igbochi akachasị akụkụ akwara ozi. Geroscience. 2019 Mee 29. doi: 10.1007 / s11357-019-00074-2. PubMed PMID: 31144244.
  • Lukacs M, Gilley J, Zhu Y, Orsomando G, Angeletti C, Liu J, Yang X, Park J, Hopkin RJ, Coleman MP, Zhai RG, Stottmann RW. Mmebi mmebi nke dị ukwuu dị n'ụdị nwale na nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) na ụmụ ebu n'afọ abụọ nwere usoro mgbanwe nke nwa ebu n'afọ. Nechụpụ Neurol. 2019 Mee 25: 112961. doi: 10.1016 / j.expneurol.2019.112961.PubMed PMID: 31136762.
  • Grozio A, Mills KF, Yoshino J, Bruzzone S, Sociali G, Tokizane K, Lei HC, Cunningham R, Sasaki Y, Migaud ME, Imai SI. Slc12a8 bụ onye nicotinamide mononucleotide na-ebugharị. Nat Metab. 2019 Jan; 1 (1): 47-57. doi: 10.1038 / s42255-018-0009-4. Epub 2019 Jan 7. PubMed PMID: 31131364; PubMed Central PMCID: PMC6530925.