Vinpocetine ntụ ntụ Smmezi
| aha: | Vinpocetine |
| CAS: | 42971-09-5 |
| ọcha | 98% |
| Usoro Molecular: | C22H26N2O2 |
| Molekụla arọ: | 350.454 g / mol |
| Melt Point: | 147-149 ° C |
| Aha aha: | AY-27255, Cavinton, Eburnamenine-14-carboxylic acid, Ethyl Apovincaminate, Ethylapovincaminoate, |
| Synonyms: | Etyl Esta, RGH-4405, TCV-3b, Vinpocetin, Vinpocetina, Vinpocétine. |
| KeyInChI: | DDNCQMVWWZOMLN-IRLDBZIGSA-N |
| Mkpochapu Ndụ: | 2.54 +/- 0.48 awa |
| Solubility: | Nsogbu na DMSO, Methanol, Mmiri |
| Ọnọdụ Nchekwa: | 0 - 4 C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 C maka ogologo oge (ọnwa) |
| ngwa: | Vinpocetine bụ onyinye sitere na osisi Periwinkle nke a na-eji dị ka ihe nchebe na-egbochi ịka nká. Otu n'ime ihe a na-ahụkarị na nootropics, Vinpocetine nwere ike ime ka ọbara gbasaa ma mee ka ọ nwekwuo ncheta; ekwupụtaghi nyocha nke ikpeazụ a. |
| anya: | White ntụ ntụ |
Vinpocetine (42971-09-5) NMR ụdịdị dị iche iche
Ọ bụrụ na ịchọrọ COA, MSDS, HNMR maka ụdị ngwaahịa ọ bụla na ozi ndị ọzọ, biko kpọtụrụ anyị njikwa ahia.
Gịnị bụ Vinpocetine (42971-09-5)?
Vinpocetine bụ sịntetik alkaloid sitere na periwinkle osisi (kpọmkwem, synthesized site na molekul a maara dị ka 'vincamine') nke na-egosi nwere usoro egwu eji eji eme ihe na mba Europe maka ọgwụgwọ nke ịda mbà n'obi, mgbake ọrịa, na akwụkwụ. A na-ejikwa Vinpocetine eme ihe dị ka ngwakọta nootropic na-enwe olileanya na ọ nwere ike ịkwalite nhazi ebe nchekwa.
Vinpocetine ntụ ntụ (42971-09-5) uru
Vinpocetine amataghị nke ọma, mana ihe na-etinye uche nke ọma n'ọbara ngwa ngwa ma dịkwa nfe banye n'ụbụrụ ebe ọ ga - arụ ọrụ ya. Njirimara ndị na-egosi na ha na-etinye na vinpocetine supplementation gụnyere neuroprotection (megide nsị na mkpali na-akpali akpali) ma belata nsị nke anụ ahụ, ebe mmetụta mmụba na-egosi na ọ bụghị nke ọma na-akwado site na ihe akaebe n'oge a. Ọ bụ ezie na vinpocetine na-egosi na ọ dị irè na-egbochi nsị ma ọ bụ nrụgide na-akpata amnesia, egosighi ya iji mepụta ncheta ebumpụta ụwa.
Vinpocetine na-egosikwa na ọ nwere mmetụta ụfọdụ megide ịda mbà n'obi, ma ọnụ ọgụgụ nke akwụkwọ ndị dị na isiokwu a dị ntakịrị karịa ọgwụ ndị ọzọ a nwalere maka nzube a (CDP-Choline ma ọ bụ Alfa-GPC na akpan akpan). Opekempe otu ọmụmụ achọpụtala mmụba na oge mmeghachi omume na mbadamba vinpocetine 40mg, nke nwere ike ịbụ otu n'ime naanị nkwalite dị mkpa maka ndị ahụ siri ike n'oge a.
Ntinye nke vinpocetine na-egosi na ọ na-eme ka ọbara na-aga ụbụrụ na-enweghị mgbatị na-agbanwe agbanwe nke ọma, nke a na-echekwa (mana egosighi) itinye aka na ingestion nke onu. Nke a nwere ike belata isi ọwụwa kpatara oke nrụgide, ọ dịkwa n'usoro ọdịnala nke osisi periwinkle (iji belata isi ọwụwa).
Vinpocetine (42971-09-5) ngwa?
Usoro nke vinpocetine dị ọtụtụ. Ọ dị ka ya na ọtụtụ ọwa ion (sodium, potassium, na calcium) na-emekọrịta ka ọ na-ebute nsonaazụ nrụgide na ntọhapụ neurotransmitter na neuroprotection mgbe a na-egbochi dopamine ma ọ bụ glutamate (ndị a, mgbe toxins kpaliri n'ụzọ na-enweghị isi, nwere ike ibute mmebi oxidative). Ọ na - esokwa ndị na - anabata alpha adrenergic na ndị na - anabata TPSO, yana ezigbo uru nke ndị na - anabata nnabata a apụtaghị na ha nwere ike ịdị mkpa ebe ọ bụ na ha na - eme otu uche na mmekọrịta ion channel.
Vinpocetine bụkwa onye na-egbochi PDE1, nke bụ usoro nke na-eme ka obi dịkwuo elu na nke uche. O di nwute, mmachi a na-eme n'ogo buru ibu ma ọ nwere ike ọ gaghị emetụta ọkọlọtọ mgbakwunye doses nke vinpocetine.
Yiri nke PDE1, ikike antinpaminergic nke vinpocetine na mgbochi mgbochi nke ndị na-anabata glutaminergic ha abụọ na-eme na nnukwu ịta ahụhụ na vitro ma ọ nwere ike ọ gaghị adị mkpa na mgbakwunye mgbakwunye.
Vinpocetine (42971-09-5) Ọnụọgụ ọgwụ
A na-ewere Vinpocetine n'ụdị usoro ọgwụgwọ kwa ụbọchị nke 15-60mg, kewara n'ime usoro atọ kwa ụbọchị na nri. Lowkpụrụ dị ala bụ 5mg na nke ọ bụla n'ime nri atọ a, na 20mg na nri ọ bụla a hụrụ dị ka njedebe dị elu nke nrụpụta. A na-ewere usoro a maka ebumnuche nke neuroprotection, na-eme ka ụbụrụ ọbara na-arịwanye elu, ma na-ebelata ọnụ ọgụgụ nke ịda mbà.
Ihe na njedebe dị elu nke ụdị ahụ (30-45mg nnukwu dosages) nwere ike ịba uru maka ịkwalite cognition na ncheta ncheta na ndị ọzọ ahụike, mana enweghị ọtụtụ ihe akaebe na-ele anya nkwupụta a.
Dọ aka ná ntị: maka ụmụ nwanyị dị ime, ihe nha anya nke 10 mg / d jikọtara na nsị nke nwa ebu n'afọ na ọmụmụ anụmanụ. 10 mg / d nwekwara ike ịdị ize ndụ, ọkachasị mgbe ị na-ewere ime n'afọ niile.
Vinpocetine powder n'ihi na ire(Ebe ịzụta Vinpocetine ntụ ntụ na nnukwu)
Ụlọ ọrụ anyị na-enwe mmekọrịta ogologo oge na ndị ahịa anyị n'ihi na anyị na-elekwasị anya na ọrụ ndị ahịa na inye nnukwu ihe ngwaahịa. Ọ bụrụ na i nwere mmasị na anyị ngwaahịa, anyị na-agbanwe na customization nke iwu ona gị kpọmkwem mkpa na anyị ngwa ngwa ụzọ oge na iwu emesi ị ga-enwe oké akatabi okop ngwaahịa anyị na-oge. Anyị na-elekwasịkwa anya na ọrụ ndị bara uru. Anyị dị maka ajụjụ ọrụ na ozi iji kwado azụmahịa gị.
Anyị bụ ndị ọkachamara Vinpocetine ntụ ntụ soplaya ruo ọtụtụ afọ, anyị na-enye ngwaahịa na asọmpi ọnụahịa, ngwaahịa anyị kachasị mma ma na-anwale ule siri ike, nke onwe iji hụ na ọ dị mma maka oriri gburugburu ụwa.
References
- Abdel-Salam OME. Vinpocetine na piracetam na-arụ ọrụ antinociceptive na ụdị mgbu visceral na ụmụ oke. Pharmacol Rep. 2006; 58 (5): 680-691.17085860
- Akopov SE, Gabrielian ES. Mmetụta nke aspirin, dipyridamole, nifedipine na Cavinton nke na-arụ ọrụ na nchịkọta platelet nke ndị ọrụ nchịkọta dị iche iche na-ebute naanị na nchịkọta. Eur J Clin Pharmacol. Ọrịa. 1992; 42 (3): 257-259.1577042
- Alkuraishy HM, Al-Gareeb AI, Albuhadilly AK. Vinpocetine na pyritinol: ihe omuma ohuru maka imeghari ogwu nke ọbara na oria cerebrovascular-omumu omumu omumu. Ihe Biomed Res Int. 2014; 2014: 324307.25548768.
