Coluracetam (135463-81-9)

Coluracetam (135463-81-9) Smmezi

Coluracetam (135463-81-9) NMR ụdịdị dị iche iche

Ọ bụrụ na ịchọrọ COA, MSDS, HNMR maka ụdị ngwaahịa ọ bụla na ozi ndị ọzọ, biko kpọtụrụ anyị njikwa ahia.

Gịnị bụ Coluracetam (135463-81-9)?

Ụkwụ Coluracetam nke ụkọ (MKC-231) bụ ọgwụ ọgwụ racetam nke sịntetị bụ nke a na-ekwu na ọ bụ ihe na-enweghị atụ. O nweghị nnukwu ihe àmà nke na - achọpụta ya, ma usoro nke ihe (ma ọ bụ usoro) dị iche site na mpaghara ndị ọzọ racetam dị ka Piracetam ma ọ bụ Aniracetam.

Raw Coluracetam ntụ ntụ na-egosi na ọ na-emekọ ihe na usoro a maara dị ka elu affinity choline uptake (HACU maka mkpụmkpụ), nke bụ njedebe nke njedebe nke ịbịaru choline n'ime neuron maka njikọ n'ime neurotransmitter acetylcholine. Ịba ụba ọnụego HACU yiri ka ọ na-abawanye ọrụ nke neurons cholinergic, yabụ na ọ bụ ebumnuche achọrọ maka ya. nkwalite ọgụgụ isi.

Coluracetam (135463-81-9) uru

• Nwee ebe nchekwa na mmụta
• Meziwanye nghota na ighota ihe
• Ntughari uche ogologo oge
• Belata Mbelata Ọgwụgwọ
• Nwere ike ịkwalite Neurogenesis
• Nwere ike melite nsogbu ụbụrụ
• Nwere ike Mee Ọhụụ
• Ahụhụ nrịba ọria
• Ojiji ntụrụndụ Coluracetam

Coluracetam (135463-81-9) ojiji

Coluracetam (INN) (koodu aha BCI-540; nke mbụ MKC-231) ntụ ntụ bụ onye ọrụ nootropic nke ezinụlọ racetam. Ndị Mitsubishi Tanabe Pharma Corporation mepụtara ya na mbụ maka ọrịa Alzheimer. Mgbe ọgwụ ahụ eruteghị njedebe n'ime ule ụlọ ọgwụ ya, BrainCells Inc nyere ikike maka nyocha banyere nnukwu nsogbu ịda mbà n'obi (MDD), bụ nke e bu ụzọ nye ya "Gụntụ Mmemme Nchọpụta Ọgwụgwọ Ahụike" site na steeti California.

Coluracetam (135463-81-9) Ọnụọgụ ọgwụ

Ihe ka ukwuu n'ime nnyocha ndị e mere na coluracetam mere na ụmụ anụmanụ karịa ụmụ mmadụ, n'ihi ya, ọ dịghị usoro nduzi nduzi ọ bụla a nakweere. A na-akọwakarị ụdị usoro ọgwụgwọ dịka 5-20 mg. Ndị ọrụ nke coluracetam ekwuwo ọtụtụ usoro a na-eji edozi ọnụ ma jiri nwayọọ.

Nzaghachi onye ọrụ ekwuola na ndidi na coluracetam ntụ ntụ nwere ike ịmalite ngwa ngwa. Dị ka ọgwụ niile, ọkachasị nootropics, ọ kachasị mma ịmalite na obere obere wee jiri nwayọ nwayọ nwayọ ka ahụ gị na-eme ma gbanwee ọgwụ ahụ. Coluracetam anaghị egbu egbu ma na-ahụta ka edobere ya nke ọma.

Coluracetam ntụ ntụ n'ihi na ire(Ebe Buyzụta Coluracetam ntụ ntụ na nnukwu)

Ụlọ ọrụ anyị na-enwe mmekọrịta ogologo oge na ndị ahịa anyị n'ihi na anyị na-elekwasị anya na ndị ahịa ọrụ na inye nnukwu ngwaahịa. Ọ bụrụ na i nwere mmasị na anyị ngwaahịa, anyị na-agbanwe na customization nke iwu ona gị kpọmkwem mkpa na anyị ngwa ngwa ụzọ oge na iwu emesi ị ga-enwe oké akatabi okop ngwaahịa anyị na-oge. Anyị na-elekwasịkwa anya na ọrụ ndị bara uru. Anyị dị maka ajụjụ ọrụ na ozi iji kwado azụmahịa gị.

Anyị bụ ndị ọkachamara Coluracetam ntụ ntụ soplaya ruo ọtụtụ afọ, anyị na-enye ngwaahịa na asọmpi ọnụahịa, na ngwaahịa anyị bụ nke kachasị mma ma na-enweta nyocha siri ike, nke onwe ya iji hụ na ọ dị mma maka oriri gburugburu ụwa.

References

[1] Akaike A, et al. (1998). Ihe nchedo nke MKC-231, ihe nnochi anya choline uptake enhancer, na glutamate cytotoxicity na ozuzu cortical akwara ozi. Jpn J Pharmacol.

[2] Bessho, T., Takashina, K., Tabata, R., Ohshima, C., Chaki, H., Yamabe, H., Egawa, M., Tobe, A., & Saito, K. (1996). Mmetụta nke akwụkwọ akụkọ a dị elu choline uptake enhancer 2- (2-oxopyrrolidin-1-yl) -N- (2,3-dimethyl-5,6,7,8-tetrahydrofuro [2,3-b] quinolin-4- yl) acetoamide na mpe nke mmiri maze mmụta na oke. Arzneimittel-Forschung, 46 (4), 369-373.

[3] Murai, S., Saito, H., Abe, E., Masuda, Y., Odashima, J., & Itoh, T. (1994). MKC-231, ihe nkwalite choline, na-eme ka ncheta ncheta na-arụ ọrụ ma belata hippocampal acetylcholine nke ethylcholine aziridinium ion kpatara. Akwụkwọ nke Neural Transmission, 98 (1), 1-13. Doi: 10.1007 / bf01277590.

[4] Takashina K, Bessho T, Mori R, Eguchi J, Saito K. MKC-231, onye na-akwalite choline: (2) Mmetụta na njikọta na ntọhapụ nke acetylcholine na oke ejiri agwọ ọrịa AF64A. J Neural Transm (Vienna). 2008 Jul; 115 (7): 1027-35. doi: 10.1007 / s00702-008-0048-1. PubIDed PMID: 18446264.

[5] Shirayama Y, Yamamoto A, Nishimura T, Katayama S, Kawahara R. Nkpughe na-esote na nkwalite choline uptake MKC-231 antagonizes ntụpọ omume arụmọrụ phencyclidine na mbelata na septal cholinergic neurons na oke. Eur Neuropsychopharmacol. 2007 Septemba; 17 (9): 616-26. PubIDed PMID: 17467960.

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