Kachasị mma Coluracetam (135463-81-9) Emeputa - Cofttek

Coluracetam (135463-81-9)

Nwere ike 8, 2021

Cofttek bụ Coluracetam ntụ ntụ kacha mma na China. Ụlọ ọrụ anyị nwere sistemụ njikwa mmepụta zuru oke (ISO9001 & ISO14001), yana ikike mmepụta kwa ọnwa nke 160kg.

 


ọnọdụ: Na Production Production
Otu: 1kg / akpa, 25kg / Drum

Coluracetam (135463-81-9) Smmezi

aha: Coluracetam
CAS: 135463-81-9
ọcha 98%
Usoro Molecular: C19H23N3O3
Molekụla arọ: 341.411 g / moll
Melt Point: N / A
Aha aha: N-(2,3-dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide

MKP-231

Bci-540

Synonyms: Coluracetam; BCI-540; MKC-231; BCI 540; MKC 231; BCI540; MKC231.
KeyInChI: PSPGQHXMUKWNDI-UHFFFAOYSA-N
Ọkara ndụ: N / A
Solubility: Soluble na DMSO
Ọnọdụ Nchekwa: Akọrọ, ọchịchịrị na 0 - 4 C maka obere oge (ụbọchị ruo izu) ma ọ bụ -20 C maka ogologo oge (ọnwa ruo afọ)
ngwa: Ụkwụ Coluracetam nke ụkọ (MKC-231) bụ ọgwụ ọgwụ racetam nke sịntetị bụ nke a na-ekwu na ọ bụ ihe na-enweghị atụ.
anya: ọcha crystalline ntụ ntụ

 

Coluracetam (135463-81-9) NMR ụdịdị dị iche iche

Coluracetam (135463-81-9) NMR ụdịdị dị iche iche

Ọ bụrụ na ịchọrọ COA, MSDS, HNMR maka ụdị ngwaahịa ọ bụla na ozi ndị ọzọ, biko kpọtụrụ anyị njikwa ahia.

 

Gịnị bụ Coluracetam (135463-81-9)?

Ụkwụ Coluracetam nke ụkọ (MKC-231) bụ ọgwụ ọgwụ racetam nke sịntetị bụ nke a na-ekwu na ọ bụ ihe na-enweghị atụ. O nweghị nnukwu ihe àmà nke na - achọpụta ya, ma usoro nke ihe (ma ọ bụ usoro) dị iche site na mpaghara ndị ọzọ racetam dị ka Piracetam ma ọ bụ Aniracetam.

Ụkwụ Coluracetam dị elu na-egosipụta ka ọ na-emekọrịta na usoro a maara dị ka ebido ịchọta ịchọta afụcha (HACU maka mkpụmkpụ), nke bụ nkwụsịtụ nke na-agbatị ọnụ maka ịbịpụta ihe na ntinye maka ntinye aka n'ime acetylcholine neurotransmitter. Ịbawanye ọnụego HACU na-egosi ka ịmalite ọrụ nke eriri cholinergic, ya mere, ọ bụ ihe mgbaru ọsọ a chọrọ maka mmelite nke uche.

 

Coluracetam (135463-81-9) uru

  • Nwee ebe nchekwa na mmụta
  • Meziwanye nghota na ighota ihe
  • Ntughari uche ogologo oge
  • Belata Mbelata Ọgwụgwọ
  • Nwere ike ịkwalite Neurogenesis
  • Nwere ike melite nsogbu ụbụrụ
  • Nwere ike Mee Ọhụụ
  • Ahụhụ nrịba ọria
  • Ojiji ntụrụndụ Coluracetam

 

Coluracetam (135463-81-9) ojiji

Coluracetam (INN) (aha koodu BCI-540; nke a na-akpọbu MKC-231) uzuzu bụ onye nootropic na-elekọta ezinụlọ racetam. Ebu ụzọ Mitsubishi Tanabe Pharma Corporation mepụtara ma nwalee ya maka ọrịa Alzheimer. Mgbe ọgwụ ahụ na-enweghị ike iru njedebe na ọnwụnwa ahụike ya, BrainCells Inc nyere ya ikikere maka nyocha n'ime nnukwu ndagide nsogbu (MDD), bụ nke bu ụzọ nweta onyinye "Qualifying Therapeutic Discovery Program Grant" site na steeti California.

 

Coluracetam (135463-81-9) Ọnụọgụ ọgwụ

Ihe ka ukwuu n'ime nnyocha ndị e mere na coluracetam mere na ụmụ anụmanụ karịa ụmụ mmadụ, n'ihi ya, ọ dịghị usoro nduzi nduzi ọ bụla a nakweere. A na-akọwakarị ụdị usoro ọgwụgwọ dịka 5-20 mg. Ndị ọrụ nke coluracetam ekwuwo ọtụtụ usoro a na-eji edozi ọnụ ma jiri nwayọọ.

Nzaghachi onye ọrụ ekwuola na ndidi na coluracetam ntụ ntụ nwere ike ịmalite ngwa ngwa. Dị ka ọgwụ niile, ọkachasị nootropics, ọ kachasị mma ịmalite na obere obere wee jiri nwayọ nwayọ nwayọ ka ahụ gị na-eme ma gbanwee ọgwụ ahụ. Coluracetam anaghị egbu egbu ma na-ahụta ka edobere ya nke ọma.

 

Coluracetam ntụ ntụ n'ihi na ire(Ebe Buyzụta Coluracetam ntụ ntụ na nnukwu)

Companylọ ọrụ anyị na ndị ahịa anyị na-enwe mmekọrịta ogologo oge n'ihi na anyị na-elekwasị anya n'ọrụ ndị ahịa ma na-enye nnukwu ngwaahịa. Ọ bụrụ na ị nwere mmasị na ngwaahịa anyị, anyị na-agbanwe agbanwe na nhazi nke iwu iji kwekọọ na mkpa gị kpọmkwem na oge ngwụsị nke oge anyị na ntinye iwu nke nkwa ị ga-enwe nnukwu uto nke ngwaahịa anyị n'oge. Anyị na-elekwasịkwa anya n'ọrụ bara uru. Anyị dị maka ajụjụ ọrụ na ozi iji kwado azụmahịa gị.

Anyị bụ ndị ọkachamara Coluracetam ntụ ntụ soplaya ruo ọtụtụ afọ, anyị na-enye ngwaahịa na asọmpi ọnụahịa, ngwaahịa anyị nwere nke kachasị mma ma na-anwale ule siri ike, nke onwe iji hụ na ọ dị mma maka oriri gburugburu ụwa.

 

References

[1] Akaike A, et al. (1998). Ihe nchedo nke MKC-231, ihe nnochi anya choline uptake enhancer, na glutamate cytotoxicity na ozuzu cortical akwara ozi. Jpn J Pharmacol.

[2] Bessho, T., Takashina, K., Tabata, R., Ohshima, C., Chaki, H., Yamabe, H., Egawa, M., Tobe, A., & Saito, K. (1996). Mmetụta nke akwụkwọ akụkọ a dị elu choline uptake enhancer 2- (2-oxopyrrolidin-1-yl) -N- (2,3-dimethyl-5,6,7,8-tetrahydrofuro [2,3-b] quinolin-4- yl) acetoamide na mpe nke mmiri maze mmụta na oke. Arzneimittel-Forschung, 46 (4), 369-373.

[3] Murai, S., Saito, H., Abe, E., Masuda, Y., Odashima, J., & Itoh, T. (1994). MKC-231, ihe nkwalite choline, na-eme ka ncheta ncheta na-arụ ọrụ ma belata hippocampal acetylcholine nke ethylcholine aziridinium ion kpatara. Akwụkwọ nke Neural Transmission, 98 (1), 1-13. Doi: 10.1007 / bf01277590.

[4] Takashina K, Bessho T, Mori R, Eguchi J, Saito K. MKC-231, onye na-akwalite choline: (2) Mmetụta na njikọta na ntọhapụ nke acetylcholine na oke ejiri agwọ ọrịa AF64A. J Neural Transm (Vienna). 2008 Jul; 115 (7): 1027-35. doi: 10.1007 / s00702-008-0048-1. PubIDed PMID: 18446264.

[5] Shirayama Y, Yamamoto A, Nishimura T, Katayama S, Kawahara R. Nkpughe na-esote na nkwalite choline uptake MKC-231 antagonizes ntụpọ omume arụmọrụ phencyclidine na mbelata na septal cholinergic neurons na oke. Eur Neuropsychopharmacol. 2007 Septemba; 17 (9): 616-26. PubIDed PMID: 17467960.

 


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